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Griepvirus of angstvirus?
Het virus dat zich momenteel het snelst verpreidt, is niet het griepvirus. Het 'swine flu'-virus mag dan wel heel wat mensen treffen, dat aantal blijft voorlopig te beperkt om van een pandemie te spreken. Elk jaar zijn er griepgolven, en die maken slachtoffers, vooral bij risicogroepen. Maar deze variant treft vooral de minst zwakke risicogroep, en dat verontrust de wetenschappers.
De Wereldgezondheidsorganisatie heeft net het gevaarniveau van deze griepvariant verhoogd. Enkele Q&A via
CNN
zijn interessant:
CNN:
Another question that we have we haven't gotten to, actually, which is an important question, also on Twitter. "If a person has had the flu shot this year, is he or she protected? Does this person have a better chance of getting it, or would it just be a milder case?" Thank you.
Gupta:
Well, it doesn't appear that the flu shot really offers much in the way of protection, although it may offer some, and here's why.
This particular virus seems to be
a combination of several different strains: two strains of swine flu, one strain of bird flu and one strain of human flu.
It's the human flu that that flu shot may protect slightly against. So you're protecting against a part of the virus if that makes any sense.
But it's a very good idea to get your flu shot, for sure. Always think about that. But in terms of protecting for swine flu, it's not going to be enough.
CNN:
We've got another question ... via Twitter this morning. And this is a question, of course, everybody is wanting to know the answer to: "Could this strain get out of control and mutate into something similar to the 1918 pandemic?"
Gupta:
Well, when you look at pandemics, they have several different qualities. They're usually a virus or some sort of pathogen the world has never seen before. They cause a lot of death, and they're sustainable in populations. We know that this is a new virus.
It is very hard to figure out just how deadly this is yet. We know that over 100 people have died here in
Mexico
, but we don't know out of how many people who got sick. There are about 1,300 people who had serious illness, but there may be thousands more who had mild illness who never went to the hospital. So it's hard to tell how lethal this is.
So, you know, on one hand, in 1918, you didn't have global air travel. Nowadays, you do. So this virus can move around the world a lot faster. But right now, it doesn't seem like it's as lethal. You know, it's just early in this whole process to be able to tell.
CNN:
Sanjay, one question that we haven't gotten to ... most of the people who died from swine flu in Mexico were in the prime of their lives really, and this usually hits infants or the elderly. What does that say to you as a doctor?
Gupta:
This is interesting. And the same thing happened in sort of a nonintuitive way when we were talking about SARS and when we were talking about avian flu.
Think about it like this: Typically, you think of someone who has a weakened immune system, who's going to be most adversely affected by an infection. Their immune system simply can't fight it.
But in these cases, it's the immune system itself that reacts robustly, and it's the immune system in that reaction to the virus that is causing death in these patients. So the virus starts that cascade, but all that fluid builds up in the lungs, and all those inflammatory cells throughout the body -- that's what's causing the problem. We saw the same thing with SARS and with avian flu as well.
Which is why exactly as you said ... [people in their] 20s and 30s and 40s, this hospital behind me, they say that's been the bulk of their patients with regard to swine flu.
CNN:
You know, Sanjay, everybody knows that you're the sort of doctor that gets out there in the thick of things whenever something happens around the world -- any kind of public health emergency or disaster. And you're there in Mexico City, and a lot of people at home might be thinking, why the heck would Dr. Gupta want to go to a place where there's disease outbreak. What are you doing to protect yourself?
Gupta:
Well, we are trying to -- you know, we're clearly being very cautious here. We're not taking any chances. These masks can be helpful. But, you know, this is going to sound simple, but simply washing our hands. This is a virus that lives on keyboards, lives on money. We don't shake hands with people. That's the way it's probably being spread, and that's what we're trying to avoid.
But this is where it started. If we figure out what happened here, we may figure out what happened in the rest of the world.
Wat we dus weten is dat deze griep geen varkensgriep is, maar een kruising van een kip, een varken en een mens. Suggesties voor een naam mogen bij de comments gevoegd worden.
Tot nu toe is het griepvirus dus nog niet ernstiger gebleken dan andere griepepidemies. Maar de vrees bestaat dat het erger wordt. Als SARS (de Chinese 'griep', maar beter gezegd longontsteking in 2002-2003) iets heeft aangetoond, dan is het dat de angst werd overdreven. Er waren al bij al iets meer dan 100 overlijdens.
Jaarlijks zouden in Nederland alleen al meer dan 1000 mensen overlijden aan de gewone griepvirussen. De paniek over deze griepvariant is dus minstens overdreven.
Wat opvalt, is dat deze paniekgolf over de pandemie zo sterk gelijkt op
een van de risicoscenario's van het Global Risk Report van 2007 (zie extract in DS onder). Dat werd opgesteld door het WEF, world economic forum.
http://www.weforum.org/pdf/CSI/Global_Risks_2007.pdf
Dat scenario kunt u nalezen, en oogt niet fraai.
En sinds het financiële virus en de crisis die het veroorzaakte, kan je niet zeggen dat zo'n scenario niet kan. Pandemies zijn inderdaad van alle tijden, net zoals financiële crisissen.
Voorlopig zijn we echter nog niet zo ver, en is het angstvirus een grotere bedreiging voor de wereldeconomie dan het (varkens)griepvirus.
18 Comments
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Ann Moons
On 27 Apr, 2009
De impact van SARS was beperkt op de volksgezondheid, maar als ik me niet vergis was de economische schade toch aanzienlijk.
Misschien hebben anderen gedetailleerde info ?
Ik meende te herinneren dat het in China een mini-recessie veroorzaakte (?)
Mexico is wel een minder belangrijke economie, maar elke vorm van paniek in de VS of Europa kan toch het herstel bemoeilijken.
Heeft iemand een idee hoe lang het zal duren voor we zicht hebben op de besmetting en de kans op een pandemie ? -
Peter Martens
On 27 Apr, 2009
SARS was tussen oktober 2002 en de lente van 2003, en viel samen met het dieptepunt van de markten.
De sfeer was dezelfde als vandaag: erg somber, en iedereen zag het als de druppel te veel. -
koen2
On 27 Apr, 2009
Er zijn bij mijn weten geen varkens besmet, noch kippen, enkel mensen. In een van de grootste en dichtst bevolkte steden ter wereld. En de mutatie gebeurde tijdens het griepseizoen. Dit is dus een mensenvirus. Maar ja, mochten het in België uitgebroken zijn, we zouden ook niet spreken over de Belgische griep...
Ik denk dat er van paniek geen sprake is. Zelfs niet in Mexico city. Maar de ongerustheid is wel degelijk gerechtvaardigd:
Stealing the limelight from our officially appointed assassin, H5N1, this porcine virus is a threat of unknown magnitude. It seems less lethal than Sars in 2003, but as an influenza it may be more durable than Sars. Given that domesticated seasonal type-A influenzas kill as many one million people a year, even a modest increment of virulence, especially if combined with high incidence, could produce carnage equivalent to a major war.
http://www.guardian.co.uk/commentisfree/2009/apr/27/swine-flu-mexico-health
Ook opvallend, de cirkel is rond:
Since its identification during the Great Depression, H1N1 swine flu had only drifted slightly from its original genome. Then in 1998 a highly pathogenic strain began to decimate sows on a farm in North Carolina and new, more virulent versions began to appear almost yearly, including a variant of H1N1 that contained the internal genes of H3N2 (the other type-A flu circulating among humans).
Researchers interviewed by Science worried that one of these hybrids might become a human flu (both the 1957 and 1968 pandemics are believed to have originated from the mixing of bird and human viruses inside pigs), and urged the creation of an official surveillance system for swine flu: an admonition, of course, that went unheeded in a Washington prepared to throw away billions on bioterrorism fantasies. -
koen2
On 27 Apr, 2009
@Ann:
Ik denk dat we ergens tss fase 5 en 6 zitten:
http://www.cdc.gov/flu/pandemic/phases.htm
da's, me dunkt, een cruciale vraag: gaat het virus zich verspreiden vanuit mensen die besmet uit Mexico terugkwamen? en verliest het daarbij aan virulentie?
wat dit betreft lijkt het voorlopig goed mee te vallen (hout vasthouden)
een Schots koppel had bvb. al met 22 mensen contact gehad, vooraleer ze in quarantaine geplaatst werden, 9 ervan vertoonden volgens de bbc lichte, griepachtige symptomen
een pandemie werd al jaren voorspeld door experts, als die dan toch onvermijdelijk is, laten we dan hopen dat dit die pandemie is (gesteld dat het dodenpercentage niet even hoog oploopt als in Mexico city, wanneer het aantal geïnfecteerden buiten Mexico verder oploopt) -
Theo
On 28 Apr, 2009
Idioms are funny things.
"If you live long enough, you'll see everything"
"When hell freezes over"... it did snow in Last Vegas this past February
"When pigs fly"...
I'm voting for "flying pig" virus -
Bart
On 28 Apr, 2009
Let's not sow panic but it just flu over.
http://www.discourse.net/archives/pix/flying_pig.jpg -
koen2
On 28 Apr, 2009
flying pig virus zou niet eens zo'n slechte benaming zijn, de ziekte blijkt namelijk niet in mexico city maar in een dorp ontstaan te zijn, en er zouden, naast varkens, ook vliegen mee gemoeid kunnen zijn:
http://www.guardian.co.uk/world/2009/apr/27/swine-flu-search-outbreak-source
A La Gloria resident who spoke to the Guardian on condition of anonymity yesterday described how illness swept through the village. "Some people started getting ill in February and an eight-month-old baby died," she said. "After that another baby died on 21 March. Suddenly most of the village got ill. It was weekend and the tiny clinic here was closed. The state health authorities then did send doctors and nurses to look after us, and give us medication. About 60% of the village were ill and we asked them what it was and they said it was a severe and atypical cold. We talked about influenza and they said that was impossible, that influenza had been eradicated from Mexico."
Smithfield, which is led by pork baron Joseph W Luter III, has previously been fined for environmental damage in the US. In October 2000 the supreme court upheld a $12.6m (£8.6m) fine levied by the US environmental protection agency which found that the company had violated its pollution permits in the Pagan River in Virginia which runs towards Chesapeake Bay. The company faced accusations that faecal and other bodily waste from slaughtered pigs had been dumped directly into the river since the 1970s .
The outbreak of respiratory illness in the area of the Granjas Carroll plant was first detected at the beginning of this month by Veratect, a company based in Washington state which monitors the spread of disease and pandemics around the world for corporate clients. -
koen2
On 28 Apr, 2009
http://www.guardian.co.uk/world/2009/apr/28/swine-flu-virus
There is no clear explanation of why the virus has killed only in Mexico. There is a chance that those who died already had other infections, or simply received worse healthcare. It is also possible that the virus was more virulent when it emerged, and has now mutated into a more transmissible, but less potent, strain.
...
Fresh vaccines to combat the infection could take between four and six months, by which time the first wave of the disease could be over. In 1918, when Spanish flu killed tens of millions, there were two subsequent waves, which were far more lethal than the first. -
Ann Moons
On 28 Apr, 2009
Ik stem me voor flying pig virus.
Verder zie ik al veel nota's verschijnen bij de banken over het virus. Allerlei gevolgen voor de beurzen enzo. Het is voor de beurshandelaren hen dus al een business geworden.
Op mijn desk liggen nu al een hoop paniekrapporten. -
koen2
On 28 Apr, 2009
we hebben een virus waarvan het nog niet zeker is dat het zich buiten mexico ver gaat verspreiden via mensen die het in mexico opdeden én dat bovendien buiten mexico, om onduidelijke redenen, zeer 'braaf' en niet dodelijk is
voorlopig is het, buiten mexico stad, dus idd meer een media virus dan wat anders:
What's in a name? The term swine flu is misleading, the EU health commissioner Androulla Vassiliou and should be renamed "novel flu" to avoid damaging the pork industry.
Others agree. The respected ProMed-mail is going for the long-winded "Influenza A (H1N1) virus, human" because it is not being spread by pigs.
An Israeli minister suggested that swine flu is not kosher and is calling it Mexico flu, to the concern of officials in Mexico.
Others suggest "media flu" would be a better term.
http://www.guardian.co.uk/news/blog/2009/apr/28/swine-flu -
koen2
On 28 Apr, 2009
http://news.bbc.co.uk/2/hi/health/8022102.stm
PROFESSOR JOHN OXFORD, VIROLOGY EXPERT AT BARTS AND THE LONDON
If the avian flu H5N1 virus had spread from human to human like this then I would be extremely worried. It would be top of my Richter scale.
But this swine flu worries me less because as a population we have a basic immunity to H1N1. Outside of Mexico there have been no deaths, so it doesn't seem so aggressive.
And not only are we coming up to the summer, which makes it less likely for these viruses to spread as well, but Britain has enough antiviral drugs for half of the population.
So we should not panic in any way. This does not look as though it is going to be a virus that sweeps the world and causes huge mortality. -
Grumpy Old Man
On 28 Apr, 2009
The Male Chauvinist Pig Virus. It covers the human and pig elements, and since they are always talking about "chicks", that part is covered to.
-
koen2
On 28 Apr, 2009
oeps:
http://www.guardian.co.uk/world/2009/apr/28/swine-flu-who-pandemic-usa-mexico
The World Health Organisation has called on all governments to prepare for a swine flu pandemic and warned that if the disease takes hold across the globe it could prove a disaster for the world's poorest countries.
"Even if activity goes down and quiet over the next few weeks, I think it would be very hard to know if it has disappeared," he said. Fukuda noted that the 1918 flu pandemic was not initially taken seriously, fell in to a lull for a few months and then returned to claim millions of lives.
Maar tegen dan zouden we een vaccin hebben (vraag is wel of het bij de tweede, dodelijke golf nog om 't zelfde virus zou gaan):
US health officials say a swine flu vaccine could be ready early next month but it will still take several months to complete safety tests, manufacture and distribute. -
Theo
On 28 Apr, 2009
Flying pig flu... as the theory goes, the pig got it from the bird and the pig transfered the flu over to humans (they have the same body temperature).
Following the Fortis GM and the flu pandemic... the strategist in me can't help it but see the analogy: Risk!
The financial crisis is at the core the result of the misguided belief that risk could be contained, even eliminated from the equation. In reality what risk management (the derivatives designed for that purpose) does is merely diffuse the risk and transfer it to someone else.
At some point in the history of pandemics we have decided to develop vaccines, both for humans and animals. All that has done has been to diffuse the risk. Today we have a virus which is not only a combination but also a mutation (mutations happen at a much faster rate since we developed vaccines). We have different generations which have had different vaccines and different resistance to the current flu.
Our reaction? develop a new vaccine... which by definition will be obsolete by the time the next pandemic comes along. -
koen2
On 28 Apr, 2009
de 1918 pandemic startte in maart 1918 en eindigde in juni 1920
De grote piek in sterfgevallen viel eind oktober 1918, dus nog voor de wapenstilstand:
http://en.wikipedia.org/wiki/File:Spanish_flu_death_chart.png -
incognito
On 1 May, 2009
interessant artikel:
http://www.latimes.com/features/health/la-sci-swine-reality30-2009apr30,0,3606923.story?page=1
Scientists see this flu strain as relatively mild
Genetic data indicate this outbreak won't be as deadly as that of 1918, or even the average winter.
...
Though scientists have begun to relax about the initial toll, they're considerably less comfortable when taking into account the fall flu season. They remain haunted by the experience of 1918, when the relatively mild first wave of flu was followed several months later by a more aggressive wave.
The longer the virus survives, the more chances it has to mutate into a deadlier form.
"If this virus keep going through our summer," Palese said, "I would be very concerned." -
Theo
On 4 May, 2009
Update... on flying pigs!
Black swan? or old Mark from the Times is reading this blog.
http://www.timesonline.co.uk/tol/comment/columnists/guest_contributors/article6216297.ece
Flying pig disease... promises to be back soon (usually in Fall and Winter)
















